diff --git a/source/blender/editors/interface/interface_region_popover.cc b/source/blender/editors/interface/interface_region_popover.cc
index 9a2967a5cc2..46d0154fd70 100644
--- a/source/blender/editors/interface/interface_region_popover.cc
+++ b/source/blender/editors/interface/interface_region_popover.cc
@@ -75,13 +75,21 @@ struct uiPopover {
 #endif
 };
 
-static void ui_popover_create_block(bContext *C, uiPopover *pup, wmOperatorCallContext opcontext)
+/**
+ * \param region: Optional, the region the block will be placed in. Must be set if the popover is
+ *                supposed to support refreshing.
+ */
+static void ui_popover_create_block(bContext *C,
+                                    ARegion *region,
+                                    uiPopover *pup,
+                                    wmOperatorCallContext opcontext)
 {
   BLI_assert(pup->ui_size_x != 0);
 
   const uiStyle *style = UI_style_get_dpi();
 
-  pup->block = UI_block_begin(C, nullptr, __func__, UI_EMBOSS);
+  pup->block = UI_block_begin(C, region, __func__, UI_EMBOSS);
+
   UI_block_flag_enable(pup->block, UI_BLOCK_KEEP_OPEN | UI_BLOCK_POPOVER);
 #ifdef USE_UI_POPOVER_ONCE
   if (pup->is_once) {
@@ -109,7 +117,7 @@ static uiBlock *ui_block_func_POPOVER(bContext *C, uiPopupBlockHandle *handle, v
 
   /* Create UI block and layout now if it wasn't done between begin/end. */
   if (!pup->layout) {
-    ui_popover_create_block(C, pup, WM_OP_INVOKE_REGION_WIN);
+    ui_popover_create_block(C, nullptr, pup, WM_OP_INVOKE_REGION_WIN);
 
     if (pup->menu_func) {
       pup->block->handle = handle;
@@ -124,7 +132,12 @@ static uiBlock *ui_block_func_POPOVER(bContext *C, uiPopupBlockHandle *handle, v
   uiBlock *block = pup->block;
   int width, height;
 
-  UI_block_region_set(block, handle->region);
+  /* in some cases we create the block before the region,
+   * so we set it delayed here if necessary */
+  if (BLI_findindex(&handle->region->uiblocks, block) == -1) {
+    UI_block_region_set(block, handle->region);
+  }
+
   UI_block_layout_resolve(block, &width, &height);
   UI_block_direction_set(block, UI_DIR_DOWN | UI_DIR_CENTER_X);
 
@@ -348,7 +361,7 @@ uiPopover *UI_popover_begin(bContext *C, int ui_menu_width, bool from_active_but
   pup->butregion = butregion;
 
   /* Operator context default same as menus, change if needed. */
-  ui_popover_create_block(C, pup, WM_OP_EXEC_REGION_WIN);
+  ui_popover_create_block(C, nullptr, pup, WM_OP_EXEC_REGION_WIN);
 
   /* create in advance so we can let buttons point to retval already */
   pup->block->handle = MEM_cnew<uiPopupBlockHandle>(__func__);