This is not something we support currently. Before, the simulation would just
not do anything. Now there is an error message.
In theory, a limited version of that could be supported eventually but it does
not have high priority currently. The tricky aspect of supporting this is that
each simulation has a cache, can be baked etc and we need a persistent identify
for those. That's not possible if simulations can be added and removed
dynamically all the time.
Pull Request: https://projects.blender.org/blender/blender/pulls/139479
43617743af