diff --git a/source/blender/blenkernel/BKE_blender_version.h b/source/blender/blenkernel/BKE_blender_version.h
index 0a31c6e8d79..b93fc826d76 100644
--- a/source/blender/blenkernel/BKE_blender_version.h
+++ b/source/blender/blenkernel/BKE_blender_version.h
@@ -27,7 +27,7 @@
 
 /* Blender file format version. */
 #define BLENDER_FILE_VERSION BLENDER_VERSION
-#define BLENDER_FILE_SUBVERSION 39
+#define BLENDER_FILE_SUBVERSION 40
 
 /* Minimum Blender version that supports reading file written with the current
  * version. Older Blender versions will test this and cancel loading the file, showing a warning to
diff --git a/source/blender/blenloader/intern/versioning_500.cc b/source/blender/blenloader/intern/versioning_500.cc
index d1c28be01ed..124be612b38 100644
--- a/source/blender/blenloader/intern/versioning_500.cc
+++ b/source/blender/blenloader/intern/versioning_500.cc
@@ -11,6 +11,7 @@
 #include <fmt/format.h>
 
 #include "DNA_ID.h"
+#include "DNA_brush_types.h"
 #include "DNA_curves_types.h"
 #include "DNA_grease_pencil_types.h"
 #include "DNA_mesh_types.h"
@@ -1129,6 +1130,48 @@ static void do_version_remove_lzo_and_lzma_compression(FileData *fd, Object *obj
   BLI_freelistN(&pidlist);
 }
 
+static void do_version_convert_gp_jitter_values(Brush *brush)
+{
+  /* Because this change is backported into the 4.5 branch, we need to avoid performing versioning
+   * in case the user updated their custom brush assets between using 4.5 and 5.0 to avoid
+   * overwriting their changes.
+   *
+   * See #142104
+   */
+  if ((brush->flag2 & BRUSH_JITTER_COLOR) != 0 || !is_zero_v3(brush->hsv_jitter)) {
+    return;
+  }
+
+  BrushGpencilSettings *settings = brush->gpencil_settings;
+  float old_hsv_jitter[3] = {
+      settings->random_hue, settings->random_saturation, settings->random_value};
+  if (!is_zero_v3(old_hsv_jitter)) {
+    brush->flag2 |= BRUSH_JITTER_COLOR;
+  }
+  copy_v3_v3(brush->hsv_jitter, old_hsv_jitter);
+  if (brush->curve_rand_hue) {
+    BKE_curvemapping_free_data(brush->curve_rand_hue);
+    BKE_curvemapping_copy_data(brush->curve_rand_hue, settings->curve_rand_hue);
+  }
+  else {
+    brush->curve_rand_hue = BKE_curvemapping_copy(settings->curve_rand_hue);
+  }
+  if (brush->curve_rand_saturation) {
+    BKE_curvemapping_free_data(brush->curve_rand_saturation);
+    BKE_curvemapping_copy_data(brush->curve_rand_saturation, settings->curve_rand_saturation);
+  }
+  else {
+    brush->curve_rand_saturation = BKE_curvemapping_copy(settings->curve_rand_saturation);
+  }
+  if (brush->curve_rand_value) {
+    BKE_curvemapping_free_data(brush->curve_rand_value);
+    BKE_curvemapping_copy_data(brush->curve_rand_value, settings->curve_rand_value);
+  }
+  else {
+    brush->curve_rand_value = BKE_curvemapping_copy(settings->curve_rand_value);
+  }
+}
+
 void do_versions_after_linking_500(FileData *fd, Main *bmain)
 {
   if (!MAIN_VERSION_FILE_ATLEAST(bmain, 500, 9)) {
@@ -1516,6 +1559,14 @@ void blo_do_versions_500(FileData * /*fd*/, Library * /*lib*/, Main *bmain)
     }
   }
 
+  if (!MAIN_VERSION_FILE_ATLEAST(bmain, 500, 40)) {
+    LISTBASE_FOREACH (Brush *, brush, &bmain->brushes) {
+      if (brush->gpencil_settings) {
+        do_version_convert_gp_jitter_values(brush);
+      }
+    }
+  }
+
   /**
    * Always bump subversion in BKE_blender_version.h when adding versioning
    * code here, and wrap it inside a MAIN_VERSION_FILE_ATLEAST check.
diff --git a/source/blender/editors/grease_pencil/intern/grease_pencil_primitive.cc b/source/blender/editors/grease_pencil/intern/grease_pencil_primitive.cc
index 81349557efe..38ac37310a9 100644
--- a/source/blender/editors/grease_pencil/intern/grease_pencil_primitive.cc
+++ b/source/blender/editors/grease_pencil/intern/grease_pencil_primitive.cc
@@ -781,9 +781,9 @@ static wmOperatorStatus grease_pencil_primitive_invoke(bContext *C,
   BKE_curvemapping_init(ptd.settings->curve_rand_pressure);
   BKE_curvemapping_init(ptd.settings->curve_rand_strength);
   BKE_curvemapping_init(ptd.settings->curve_rand_uv);
-  BKE_curvemapping_init(ptd.settings->curve_rand_hue);
-  BKE_curvemapping_init(ptd.settings->curve_rand_saturation);
-  BKE_curvemapping_init(ptd.settings->curve_rand_value);
+  BKE_curvemapping_init(ptd.brush->curve_rand_hue);
+  BKE_curvemapping_init(ptd.brush->curve_rand_saturation);
+  BKE_curvemapping_init(ptd.brush->curve_rand_value);
 
   ToolSettings *ts = vc.scene->toolsettings;
   GP_Sculpt_Settings *gset = &ts->gp_sculpt;
diff --git a/source/blender/editors/sculpt_paint/grease_pencil_draw_ops.cc b/source/blender/editors/sculpt_paint/grease_pencil_draw_ops.cc
index 3837e671db4..50647faf064 100644
--- a/source/blender/editors/sculpt_paint/grease_pencil_draw_ops.cc
+++ b/source/blender/editors/sculpt_paint/grease_pencil_draw_ops.cc
@@ -1513,9 +1513,9 @@ static bool grease_pencil_fill_init(bContext &C, wmOperator &op)
   BKE_curvemapping_init(brush.gpencil_settings->curve_rand_pressure);
   BKE_curvemapping_init(brush.gpencil_settings->curve_rand_strength);
   BKE_curvemapping_init(brush.gpencil_settings->curve_rand_uv);
-  BKE_curvemapping_init(brush.gpencil_settings->curve_rand_hue);
-  BKE_curvemapping_init(brush.gpencil_settings->curve_rand_saturation);
-  BKE_curvemapping_init(brush.gpencil_settings->curve_rand_value);
+  BKE_curvemapping_init(brush.curve_rand_hue);
+  BKE_curvemapping_init(brush.curve_rand_saturation);
+  BKE_curvemapping_init(brush.curve_rand_value);
 
   Material *material = BKE_grease_pencil_object_material_ensure_from_brush(&bmain, &ob, &brush);
   const int material_index = BKE_object_material_index_get(&ob, material);
diff --git a/source/blender/editors/sculpt_paint/grease_pencil_paint.cc b/source/blender/editors/sculpt_paint/grease_pencil_paint.cc
index 955aadcc34f..3dfa54d349e 100644
--- a/source/blender/editors/sculpt_paint/grease_pencil_paint.cc
+++ b/source/blender/editors/sculpt_paint/grease_pencil_paint.cc
@@ -155,9 +155,9 @@ static Brush *create_fill_guide_brush()
   BKE_curvemapping_init(settings->curve_rand_pressure);
   BKE_curvemapping_init(settings->curve_rand_strength);
   BKE_curvemapping_init(settings->curve_rand_uv);
-  BKE_curvemapping_init(settings->curve_rand_hue);
-  BKE_curvemapping_init(settings->curve_rand_saturation);
-  BKE_curvemapping_init(settings->curve_rand_value);
+  BKE_curvemapping_init(fill_guides_brush->curve_rand_hue);
+  BKE_curvemapping_init(fill_guides_brush->curve_rand_saturation);
+  BKE_curvemapping_init(fill_guides_brush->curve_rand_value);
 
   fill_guides_brush->flag |= BRUSH_LOCK_SIZE;
   fill_guides_brush->unprojected_radius = 0.005f;
@@ -1179,9 +1179,9 @@ void PaintOperation::on_stroke_begin(const bContext &C, const InputSample &start
   BKE_curvemapping_init(settings->curve_rand_pressure);
   BKE_curvemapping_init(settings->curve_rand_strength);
   BKE_curvemapping_init(settings->curve_rand_uv);
-  BKE_curvemapping_init(settings->curve_rand_hue);
-  BKE_curvemapping_init(settings->curve_rand_saturation);
-  BKE_curvemapping_init(settings->curve_rand_value);
+  BKE_curvemapping_init(brush->curve_rand_hue);
+  BKE_curvemapping_init(brush->curve_rand_saturation);
+  BKE_curvemapping_init(brush->curve_rand_value);
 
   BLI_assert(grease_pencil->has_active_layer());
   const bke::greasepencil::Layer &layer = *grease_pencil->get_active_layer();
diff --git a/source/blender/editors/sculpt_paint/grease_pencil_paint_common.cc b/source/blender/editors/sculpt_paint/grease_pencil_paint_common.cc
index fc1bb27598b..d242a572917 100644
--- a/source/blender/editors/sculpt_paint/grease_pencil_paint_common.cc
+++ b/source/blender/editors/sculpt_paint/grease_pencil_paint_common.cc
@@ -80,9 +80,9 @@ void init_brush(Brush &brush)
   BKE_curvemapping_init(brush.gpencil_settings->curve_rand_pressure);
   BKE_curvemapping_init(brush.gpencil_settings->curve_rand_strength);
   BKE_curvemapping_init(brush.gpencil_settings->curve_rand_uv);
-  BKE_curvemapping_init(brush.gpencil_settings->curve_rand_hue);
-  BKE_curvemapping_init(brush.gpencil_settings->curve_rand_saturation);
-  BKE_curvemapping_init(brush.gpencil_settings->curve_rand_value);
+  BKE_curvemapping_init(brush.curve_rand_hue);
+  BKE_curvemapping_init(brush.curve_rand_saturation);
+  BKE_curvemapping_init(brush.curve_rand_value);
 }
 
 float brush_radius(const Paint &paint, const Brush &brush, const float pressure = 1.0f)