diff --git a/source/blender/windowmanager/intern/wm_event_system.cc b/source/blender/windowmanager/intern/wm_event_system.cc
index 6638a286ca4..d2d206d50bb 100644
--- a/source/blender/windowmanager/intern/wm_event_system.cc
+++ b/source/blender/windowmanager/intern/wm_event_system.cc
@@ -3183,6 +3183,11 @@ static eHandlerActionFlag wm_handlers_do_gizmo_handler(bContext *C,
   BLI_assert(gzmap != nullptr);
   wmGizmo *gz = wm_gizmomap_highlight_get(gzmap);
 
+  if (gz && ISMOUSE(event->type) && event->val == KM_PRESS) {
+    /* Remove any tooltips on mouse down. #83589 */
+    WM_tooltip_clear(C, CTX_wm_window(C));
+  }
+
   /* Needed so UI blocks over gizmos don't let events fall through to the gizmos,
    * noticeable for the node editor - where dragging on a node should move it, see: #73212.
    * note we still allow for starting the gizmo drag outside, then travel 'inside' the node. */